傅化文的個人資料 - 清華大學生命科學院

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姓名	傅化文
個人網站	http://life.nthu.edu.tw/~labfhw/

類別	專任師資
職稱	教授
單位別	分子與細胞生物研究所 / 生命科學系 / 學士班
授課領域	蛋白質化學、分子細胞生物學
研究專長	蛋白質化學、分子細胞生物學

期刊論文一覽
年度	著作	著作人
2019	Tasi, C-C., Kuo, F-T., Lee, S-B., Chang, Y-T., Fu, H-W.,2019,Endocytosis-dependent lysosomal degradation of Src induced by protease-activated receptor 1. ,FEBS Lett.*,593,5,pp504-517 (SCI)	傅化文
2019	Tasi, C-C. Chou, Y-T. and Fu, H-W.,2019,Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells.,Biochim. Biophys. Acta. Mol. Cell. Res.* ,1866,3,pp486-503 (SCI)	傅化文
2017	Kuo,T-Y., Tsai, C-C., Fu, H-W.,2017,Enhanced mutant screening in one-step PCR-based multiple site-directed plasmid mutagenesis by introduction of silent restriction sites for structural and functional study of proteins,Biological Procedures Online*,19,12, (SCI)	傅化文
2017	Hong, Z-W., Yang Y-C. Pan, T, Tzeng, H-F, Fu, H-W.,2017,Differential effects of DEAE negative mode chromatography and gel-filtration chromatography on the charge status of Helicobacter pylori neutrophil-activating protein.,PLoS One*,12,3,ppe0173632- (SCI)	傅化文
2016	Kuo, T-Y., Hong, Z-W., Tsai, C-C., Yang, Y-C., Fu, H-W.,2016,One-step negative chromatographic purification of Helicobacter pylori neutrophil-activating protein overexpressed in Escherichia coli in batch mode.,Journal of Visualized Experiments*,112,ppe54043- (SCI)	傅化文
2015	Tsai, C-C., Kuo, T-Y., Hong, Z-W., Yeh, Y-C., Shih, K-S., Du, S-Y., Fu, H-W,2015,Helicobacter pylori neutrophil-activating protein induces release of histamine and interleukin-6 through G protein-mediated MAPKs and PI3K/Akt pathways in HMC-1 cells.,Virulence*,6,8,pp755-765 (SCI)	傅化文
2015	Yang, Y-C., Kuo, T-Y., Hong, Z-W., Chang, H-W., Chen, C-C., Tsai, T-L., Fu, H-W.,2015,High yield purification of Helicobacter pylori neutrophil-activating protein overexpressed in Escherichia coli.,BMC Biotechnol.*,15,pp23- (SCI)	傅化文
2015	Chang H-Y., Cheng K-S., Liu Y-P., Hung H-F., Fu H-W.,2015,Neonatal infected subgaleal hematoma: an unusual complication of early-onset E. coli sepsis, Pediatr Neonatol. ,56,pp126-128 (SCI)	傅化文
2014	Fu, H-W,2014,Helicobacter pylori neutrophil-activating protein: From molecular pathogenesis to clinical applications,World J Gastroenterol.*,20,18,pp5294-5301 (SCI)	傅化文
2013	Shih, K-S., Lin C-C., Hung, H-F., Yang Y-C., Wang, C-A., Jeng, K-C., Fu, H-W.,2013,One-step chromatographic purification of Helicobacter pylori neutrophil-activating protein expressed in Bacillus subtilis,Plos One*,8,4,ppe60786- (SCI)	傅化文
2013	Fang,S-L., Fan, T-C., Fu, H-W., Chen, C-J., Hwang, C-S., Hung, T-J., Lin, L-Y., and Chang, D-T. M.,2013,A novel cell-penetrating peptide derived from human eosinophil cationic protein,Plos One,8,3,ppe57318- (SCI)	傅化文
2012	Hou, C-W., Lee, Y-C., Hung, H-F., Fu, H-W., Jeng, K-C,2012,Longan seed extract reduces hyperuricemia via modulating urate transporters and suppressing xanthine oxidase activity,Am J Chin Med,40,pp979-991 (SCI)	傅化文
2012	Cheng, Y-J., Fang, S., Tsaur, S-C., Chen, Y-L., Fu, H-W., Patel, N. H., and Ting, C-T.,2012,Reduction of germ cells in the Odysseus null mutant causesmale fertility defect in Drosophila melanogaster,Genes Genet. Syst.,87,pp273-276 (SCI)	傅化文
2012	Poh, Y-P., Ting, C-T., Fu, H-W., Langley C.H., and Begun D.J.,2012,Population genomic analysis of base composition evolution in Drosophila melanogaster,Genome Biol Evol.,4,pp1245-1255 (SCI)	傅化文
2011	Hung, H-F., Hou, C-W., Chen, Y-L., Lin, C-C., Fu, H-W., Wang, J-S., and Jeng, K-C.,2011,Elephantopus scaber inhibits lipopolysaccharide-induced liver injury by suppression of signaling pathways in rats.,Am J Chin Med.,39,pp705-717 (SCI)	傅化文
2008	Wang, C.A., Liu, Y.C., Du, S.Y., Lin, C.W. and Fu, H.W.,2008,Helicobacter pylori neutrophil-activating protein promotes myeloperoxidase release from human neutrophils,Biochemical and Biophysical Research Communications* ,377,1,pp52-56 (SCI)	傅化文
2008	Shu, C.V., Sun, F.C., Cho, J.H., Lin, C.C., Liu, P.F., Chen, P.Y., Chang, M.D.T., Fu, H.W. and Lai, Y.K.,2008,GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis,Journal of Cellular Physiology,215,3,pp627-635 (SCI)	傅化文
2008	Lai, C.H., Chang, Y.C., Du, S.Y., Wang, H.J., Kuo, C.H., Fang, S.H., Fu, H.W., Lin, H.H., Chiang, A.S. and Wang, W.C.,2008,Cholesterol depletion reduces Helicobacter pylori CagA translocation and CagA-induced responses in AGS cells, Infection and Immunity ,76,7,pp3293-3303 (SCI)	傅化文
2006	Lu, T.L., Kuo, F.T., Lu, T.J., Hsu, C.Y. and Fu, H.W.,2006,Negative regulation of protease-activated receptor 1-induced Src kinase activity by the association of phosphocaveolin-1 with Csk,Cellular Signalling*,18,11,pp1977-1987 (SCI)	傅化文
2006	Kuo, F.T., Lu, T.L. and Fu, H.W.,2006,Opposing effects of β-arrestin 1 and β-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1,Cellular Signalling*,18,11,pp1914-1923 (SCI)	傅化文
2006	Chang, Y.S., Lee, L.C., Sun, F.C., Chao, C.C., Fu, H.W. and Lai, Y.K.,2006,Involvement of calcium in the differential induction of heat shock protein 70 by heat shock protein 90 inhibitors, geldanamycin and radicicol, in human non-small cell lung cancer H460 cells,Journal of Cellular Biochemistry ,97,1,pp156-165 (SCI)	傅化文

研討會論文一覽
年度	會議期間	著作	著作人
2018	2018/06/02 2018/06/03	Tasi, C-C., Chou, Y-T., and Fu, H-W.*,2018,Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells. ,International Conference on Biomedical Sciences,Taichung, Taiwan.,2018/06/02-2018/06/03	傅化文
2018	2018/03/24 2018/03/25	Tasi, C-C. Chou, Y-T. and Fu, H-W.*,2018,Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells.,The 33th Joint Annual Conference of Biomedical Science,Taipei, Taiwan,2018/03/24-2018/03/25	傅化文
2015	2015/11/17 2015/11/17	Fu, H-W.*,2015,Helicobacter pylori neutrophil-activating protein: from virulence factors to potential therapeutic targets and diagnostic biomarkers.,The 3rd NTHU-NUS Bilateral Meeting: Frontiers in Molecular Biomedicine,Singapore,2015/11/17	傅化文
2015	2015/06/26 2015/06/29	Kuo, T-Y., Hong, Z-W., and Fu, H-W.*,2015,A commercial monoclonal antibody X acts as a blocking antibody to Helicobacter pylori neutrophil-activating protein.,The 15th SCBA International Symposium （2015 SCBA）,Taipei, Taiwan,2015/06/26-2015/06/29 (其他)	傅化文
2015	2015/04/11 2015/04/11	Kuo, T-Y., Chang, H-W., Chen, C-C., Fu, H-W.*,2015,A commercial monoclonal antibody X is a new tool for detecting Helicobacter pylori neutrophil-activating protein.,馬偕紀念醫院跨院際聯合學術研討會,2015/04/11	傅化文
2015	2015/03/24 2015/03/25	Kuo, T-Y. and Fu, H-W.*,2015,A commercial monoclonal antibody X is a new tool for detecting Helicobacter pylori neutrophil-activating protein,The 30th Joint Annual Conference of Biomedical Science,Taipei, Taiwan,2015/03/24-2015/03/25	傅化文
2014	2014/04/25 2014/04/27	Fu, H-W.*,2014,Regulation of cellular signaling and trafficking of Src by protease-activated receptor 1. ,BIT’s 7 Annual Protein & Peptide Conference （PepCon-2014）,Dalian, China.,2014/04/25-2014/04/27	傅化文
2012	2012/12/06 2012/12/08	Yang, Y-C. and Fu, H-W.*,2012,One-step ion-exchange purification of Helicobacter pylori neutrophil-activating protein and bioinformatic analysis of molecular interaction between HP-NAP and Toll-like receptor 2,The Taiwan Society for Biochemistry and Molecular Biology Conference in Huisun,Nantou, Taiwan,2012/12/06-2012/12/08	傅化文
2011	2011/07/30 2011/08/01	Fu, H-W.*,2011,One-step chromatographic purification and functional characterization of recombinant Helicobacter pylori neutrophil-activating protein expressed in Bacillus subtilis., 1st Annual World Congress of Microbes-2011,Beijing, China,2011/07/30-2011/08/01 (其他)	傅化文
2010	2010/06/26 2010/07/01	Du, S-Y., Fu, H-W.* ,2010,Helicobacter pylori neutrophil-activating protein （HP-NAP） activates the MAPK and PI3K/Akt pathway in human mast cells.,the 35th FEBS Congress,Gothenburg, Sweden.,2010/06/26-2010/07/01 (SCI)	傅化文
2008	2008/06/28 2008/07/01	Fu, H-W.*, Wang, C-A., Liu, Y-C., Du, S-Y.,2019,The neutrophil-activating protein of Helicobacter pylori promotes myeloperoxidase release from human neutrophils.,The 33rd FEBS Congress & 11th IUBMB Conference,Athens, Greece. ,2008/06/28-2008/07/01 (SCI)	傅化文
2007	2007/03/17 2007/03/18	Lee, P-Y., Fu, H-W.*,2019,c-Cbl-mediated protease-activated receptor 1-induced degradation of Src.,The Twenty-Second Joint Annual Conference of Biomedical Sciences,Taipei, Taiwan.,2007/03/17-2007/03/18	傅化文
2006	2006/07/19 2006/07/23	Fu, H-W.*, Jeng, K-C. G., Liu, Y-C., Liao, P-C.,2019,Histamine and leukotriene C4 release induced by Helicobacter pylori neutrophil-activating protein in rat basophilic leukemia RBL-2H3 cells.,The 11th SCBA International Symposium,San Francisco, CA, USA.,2006/07/19-2006/07/23	傅化文

其他著作

其他
1. World Biomedical Frontiers [ISSN: 2328-0166].
  參考連結
2. Global Medical Discovery [ISSN 1929-8536]
  參考連結

專利一覽
年度	專利類別	專利名稱	西元年月	專利人
2017	其他	檢測及治療胃幽門螺旋桿菌感染之抗體與方法	2017-12-00	傅化文 / 傅化文, 郭庭佑
2017	其他	Methods for diagnosing and treating Helicobacter pylori infection	2017-12-00	傅化文 / Fu, H-W. and Kuo, T-Y.
2014	其他	單步驟純化重組胃幽門螺旋桿菌嗜中性白血球激活蛋白（HP-NAP）的方法。	2014-04-00	傅化文 / 傅化文、施國順、林志昌、楊昱琪
2014	其他	Method for one-step purification of recombinant Helicobacter pylori neutrophil-activating protein.	2014-03-00	傅化文 / Fu, H-W., Shih, K-S., Lin, C-C., and Yang, Y-C.

校內榮譽一覽
得獎年度	獎項名稱	頒獎單位
107	國立清華大學教學獎勵補助	國立清華大學
106	國立清華大學教學獎勵補助	國立清華大學
104	國立清華大學教學獎勵補助	國立清華大學
103	國立清華大學教學獎勵補助	國立清華大學
102	國立清華大學教學獎勵補助	國立清華大學
100	國立清華大學教學獎勵補助	國立清華大學
99	資深優良教師	國立清華大學
99	國立清華大學教師學術卓越獎勵	國立清華大學
96	國立清華大學生命科學院教師傑出研究獎	國立清華大學生命科學院

學校名稱	國別	系所	學位	起迄年月
杜克大學 Duke University	美國	Biochemistry	博士	1993年08月 ~ 1998年05月
國立臺灣師範大學	中華民國	化學	學士	1988年10月 ~ 1993年07月

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